Is Radiation Therapy Risky for Skin Cancers?
SHOP PATIENT PORTAL PAY BILL ABOUT
logo for Sanova Dermatology
Find a Provider
Find a Provider
Search for an expert practitioner specialized in helping you with your skincare needs.
Micah Williams, PA-C
View All
Locations
Find a Location
Search for a convenient office location where you can access our services quickly and easily.
Bee Cave & Lakeway
Dripping Springs
Metairie
North Austin
Old Metairie
Pflugerville
Steiner Ranch
View All
Mohs
Mohs Surgery
Explore our Mohs surgery options for expert skin cancer treatment and care.
Medical
Medical Services
We have a wide range of services designed to address your specific skincare needs.
Conditions Acne
Actinic Keratosis
Alopecia (Hair Loss)
Basal Cell Carcinoma
Dermatitis
Eczema
Hyperhidrosis
Leg Veins
Melanoma
Psoriasis
Rosacea
Squamous Cell Carcinoma
Vascular Lesions
Warts
View All
Treatments & Procedures Accutane
Excisions
Mole Removal
Patch Testing
Photodynamic Therapy (PDT)
Scar Revision
Sclerotherapy
Subcision
View All
Aesthetic
Cosmetic Services
Our cosmetic services are tailored to remedy your skincare needs.
Conditions Acne Scarring
Brown Age Spots
Dark Circles
Lines & Wrinkles
Melasma
View All
Treatments & Procedures Botox® & Dysport®
Body Contouring
Chemical Peels
Dermal Fillers
Facials
Hand Rejuvenation
HydraFacial®
Laser Hair Removal
Laser Resurfacing
Microneedling
Platelet Rich Plasma (PRP)
Toskani Facials
View All
Research
Find a Clinical Trial
Read more about our active and upcoming clinical trials. Register today!
SCHEDULE NOW
logo for Sanova Dermatology
MENU
CLOSE
blog

What are the Risks of Radiation Therapy for Skin Cancer?

June 23rd, 2025 | By: Admin

For many patients with skin cancer, radiation therapy can be a safe, effective cancer treatment. Radiation therapy is often used to treat basal cell carcinoma, the most common form of skin cancer; squamous cell carcinoma, the second-most common form of skin cancer; and in some instances, melanoma, one of the most serious forms of skin cancer. While radiation therapy may be used alone, it is often used in concert with surgery or other cancer treatments. Melanoma in particular is usually treated first with surgery, then with radiation, chemotherapy, immunotherapy, or a combination of these.


“Radiation therapy can often cure basal cell and squamous cell carcinoma as well as significantly slow the growth of melanoma, which can buy valuable time for other treatments to come into play,” says Dr. Adam Mamelak, board certified dermatologist and skin cancer expert in Austin, Texas.


The most common form of radiation therapy used for skin cancer is known as external beam radiotherapy (ERT), or superficial radiation therapy (SRT). In this form of radiation therapy, an external radiation source is used to direct radiation to the tumor or area to be treated. The treatment process is very similar to getting an x-ray and is completely painless. Also, while an individual treatment sessions is fairly quick, patients do require several treatment sessions.


Like all forms of radiotherapy, ERT does have a number of side-effects. This includes side-effects similar to a sunburn, such as redness, itching, blistering, and scabbing in the area of treatment. The skin can breakdown and ulcerate in the treated area and require some time to heal. Patients may also experience hair loss in the treated area as well as a permanent change in skin tone or color. Other side-effects include nausea, vomiting, and fatigue.


While Dr. Mamelak has treated patients with radiation for their skin cancer, he states he is cautious to recommend this therapy for a few reasons.


“The cure rates with radiation therapy are very high, but not as high as other treatments,” says Dr. Mamelak. “Mohs surgery, for example, offers an over 99% cure rate, while radiation is not as much. If the skin cancer recurs after treatment, radiation cannot be used again in the same area. Furthermore, surgery is more difficult and healing can be much more prolonged on irradiated skin.”


Dr. Mamelak also warns of other risks with radiation therapy. “It is well established that new skin cancers can develop in irradiated areas 10 to 20 years after the initial treatment. This was not a major concern when radiation was being used in elderly patients. However, with the new trend to use radiation in younger and younger patients, history has shown that these patients may be putting themselves at risk for more skin cancers years down the road.”


Contact Us

Dr. Mamelak treats patients with skin cancer at Sanova Dermatology and the Austin Mohs Surgery Center. Trying to decide the best way to manage your skin condition? Contact us today for any questions you may have about skin cancer and its treatments.


READY TO GET STARTED?
We would love to get started on a solution that perfectly fits your needs.
SCHEDULE NOW