Yes, Radiesse is generally considered safe. It's FDA-approved and has undergone rigorous safety testing.
You may experience some redness, bruising, or swelling that should resolve within a few days.
Radiesse is FDA-approved to combine with lidocaine, a local anesthetic that can be used to make the procedure much more comfortable. Most patients find this injectable highly tolerable, but tell your doctor if you’re concerned about discomfort during or after treatment.